B4EST short course: Polygenicity and population genetics

22 June 2022

Part of the EVOLTREE Training programme

Summary: In contrast to quantitative genetics that, from the start, has been built on the assumption that evolution was inherently acting on polygenic traits, population genetics has, by and large, been a single locus affair. However, this is slowly changing and there has been a strong interest lately in developing models of change in allele frequencies that are intrinsically assuming a multilocus response to selection. The present short course will be constructed around two series of studies, that we hope, are just the beginning of exciting new developments. First, the course will present recent applications of the omnigenic model and discuss their implications for breeding and evolutionary inferences, including modelling approaches. Secondly, we will focus on a newly developed approach to infer selection from genomewide temporal change in allele frequencies. In both cases, applications to trees will be presented.

Time:  Afternoon of June 22, 2022. The course consists of 4 lectures followed by discussions

Targeted group: PhD students and postdoctoral fellows with background in population genetics and/or quantitative genetics

Place: Lisbon and web-based for one of the lectures

To register send an email to Martin.Lascoux@ebc.uu.se

Teachers: Santiago C. González-Martínez, Marina de Miguel, Juliette Archambeau, Sam Yeaman, Martin Lascoux

Programme

• Lecture 1: 13:30- 14:30 From the infinitesimal to the omnigenic model and polygenic adaptation (SCGM and MdM)

• Lecture 2: 14:30-15:30 Applications to modelling and landscape genomics (JA)

Break

• Lecture 3: 16:00-17:00 The importance of redundancy (preliminary title, SA, Zoom)

• Lecture 4: 17:00-18:00 The linked selection signature of rapid adaptation in temporal genomic data: An application to oaks (ML)

Scholarships: If you are a member of an EVOLTREE partner lab (student or permanent staff) then you can get your expenses from the training course reimbursed up to 600 Euros! See more information here: https://www.evoltree.eu/training/training-reimbursement