B4EST short course: multiomics prediction
Abdou Wade, Harold Durufl?? and Leopoldo Sanchez
INRAE Biofora : June 23, 2022
- Global context
- What do we mean by genetic architecture?
- Architecture implies interacting elements. How important and pervasive are interactions?
- 1 Multi-omic data might be the clue to inferences of interactions and architectures
- 2 Multi-omic data might be the clue to inferences of interactions and architectures
- Simply, what are the methods for multiomics integration?
- Concatenation method: advantages and disadvantages
- 1 Experimental setup
- 2 Experimental setup
- 3 Experimental setup
- 4 Experimental setup
- Results: prediction accuracy
- Results: eQTL
- Results: average change in ranking over CIS, TRANS, non-eQTL
- Results: average change in ranking VS advantage of concatenation
- Results: distribution of changes in effects
- Workflow
- Loading and processing the input data
- Compute Input distance matrix (241 x 241)
- Predictions Models
Global context
What do we mean by genetic architecture?
slide 1