Global context

What do we mean by genetic architecture?

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Architecture implies interacting elements. How important and pervasive are interactions?

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1 Multi-omic data might be the clue to inferences of interactions and architectures

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2 Multi-omic data might be the clue to inferences of interactions and architectures

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Simply, what are the methods for multiomics integration?

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Concatenation method: advantages and disadvantages

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1 Experimental setup

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2 Experimental setup

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3 Experimental setup

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4 Experimental setup

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Results: prediction accuracy

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Results: eQTL

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Results: average change in ranking over CIS, TRANS, non-eQTL

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Results: average change in ranking VS advantage of concatenation

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Results: distribution of changes in effects